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VUF11207TFA
Cat.No.:HY-115615
CASNo.:1492153-74-8
分?式:C??H??F?N?O?
分?量:584.6
作?靶点:CXCR
作?通路:GPCR/GProtein;Immunology/Inflammation
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性VUF11207TFA(Compound29)是?种CXCR7激动剂(pKi为8.1)，可诱导CXCR7的β-arrestin2募集(
pEC50为8.8)和随后的内在化(pEC50为7.9)。
IC50TargetCXCR7
8.1(pKi)
客户使?本产品发表的科研?献
?CellDeathDis.2024Jun19;15(6):434.
?CellMolLifeSci.2024Mar13;81(1):132.
Seemorecustomervalidationsonwww.MedChemE
REFERENCES
[1].WijtmansM,etal.Synthesis,modelingandfunctionalactivityofsubstitutedstyrene-amidesassmall-moleculeCXCR7agonists.EurJ
MedChem.2012May;51:184-92.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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