基本信息
文件名称：Levodropropizine-d5-S-minus-Dropropizine-d-sub-5-sub-生命科学试剂-MCE.pdf
文件大小：458.39 KB
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更新时间：2025-05-20
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文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Levodropropizine-d5

Cat.No.:HY-B1895S1

Synonyms:(S)-(-)-Dropropizine-d;DF-526-d

55

分?式:C??H??D?N?O?

分?量:241.34

作?靶点:Isotope-LabeledCompounds;HistamineReceptor

作?通路:Others;GPCR/GProtein;Immunology/Inflammation;Neuronal

Signaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Levodropropizine-d5((S)-(-)-Dropropizine-d5)是氘代标记的Levodropropizine.Levodropropizine(DF-526)

是?种具有?服活性的组胺受体抑制剂。Levodropropizine是?种有效的,良好耐受性的镇咳剂。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharma