Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
Asperenone
Cat.No.:HY-N15453
CASNo.:18810-05-4
分?式:C??H??O
分?量:278.39
作?靶点:Lipoxygenase;Fungal
作?通路:MetabolicEnzyme/Protease;Anti-infection
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Asperenone是?种15-环氧合酶(15-LOX)抑制剂，IC50为0.3mM。同时Asperenone也是?种??板聚集
抑制剂，IC50为0.23mM。Asperenone还具有抗真菌活性，可抑制致病性真菌Ophiostoma
crassivaginatum和O.piliferum的?长。Asperenone可?于??管疾病和抗感染领域的研究[1]。
IC50Target15-LOX
0.3mM(IC50)
REFERENCES
[1].SekharRaoKC,etal.Asperenone:aninhibitorof15-lipoxygenaseandofhumanplateletaggregationfromAspergillusniger[J].
Biotechnologyletters,2002,24:1967-1970.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE
1/1