基本信息
文件名称:AnCDA-IN-1-生命科学试剂-MCE.pdf
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文档摘要

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Inhibitors?ScreeningLibraries?Proteins

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AnCDA-IN-1

Cat.No.:HY-171540

CASNo.:1185081-36-0

分?式:C??H??ClN?O?

分?量:328.75

作?靶点:Fungal

作?通路:Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性AnCDA-IN-1(CompoundJ075-4187)是?种?丁质脱?酰酶(CDA)的抑制剂,具有抗真菌活性,对A.

nidulansAnCDA的IC50为4.24μM,对?物腐败真菌和植物病原真菌的最?抑菌浓度(MIC)为260μg/mL

,最?杀菌浓度(MFC)为520μg/mL。AnCDA-IN-1可?于抗真菌领域研究[1]。

REFERENCES

[1].LiuY,etal.DiscoveryofChitinDeacetylaseInhibitorsthroughStructure-BasedVirtualScreeningandBiologicalAssays.JMicrobiol

Biotechnol.2022Apr28;32(4):504-513.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师