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Rhetsinine
Cat.No.:HY-W715538
CASNo.:526-43-2
分?式:C??H??N?O?
分?量:319.36
作?靶点:AldoseReductase
作?通路:MetabolicEnzyme/Protease
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Rhetsinine是?种可在Evodiarutaecarpa中被发现的醛糖还原酶(aldosereductase)抑制剂，其IC50值为
24.1μM。Rhetsinine在100μM浓度下可显著抑制?梨醇积累，抑制率达79.3%。Rhetsinine可?于糖尿
病并发症(如糖尿病神经病变和视?膜病变)领域的研究[1]。
REFERENCES
[1].KatoA,etal.InhibitoryeffectofrhetsinineisolatedfromEvodiarutaecarpaonaldosereductaseactivity.Phytomedicine.2009Mar;16(2-
3):258-61.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师