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E3LigaseLigand-linkerConjugate176

Cat.No.:HY-172739

CASNo.:3005273-99-1

分?式:C??H??N?O?

分?量:355.43

作?靶点:PROTACLinkers

作?通路:PROTAC

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性E3LigaseLigand-linkerConjugate176是?种E3泛素酶配体-连接?偶联物(E3ligaseligand-linker

conjugate)。E3LigaseLigand-linkerConjugate176可?于合成BMS-986458(HY-172736)[1]。

REFERENCES

[1].LyndaGroocock,etal.BMS-986458aPotentialFirst-in-Class,HighlySelective,PotentandWellToleratedBCL6LigandDirected

Degrader(LDD)DemonstratesMulti-ModalAnti-TumorEfficacyfortheTreatmentofB-CellNon-HodgkinsLymphoma.Blood.Volume144,

Supplement1,5November2024,Page957.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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