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2-Iodomelatonin(Standard)

Cat.No.:HY-101176R

CASNo.:93515-00-5

分?式:C??H??IN?O?

分?量:358.17

作?靶点:MelatoninReceptor

作?通路:GPCR/GProtein;NeuronalSignaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性2-Iodomelatonin(Standard)是2-Iodomelatonin的分析标准品。本产品?于研究及分析应?。2-

Iodomelatonin是褪?激素受体1(MT1)的强效激动剂，Ki?为28pM，对MT1的选择性是MT2的5倍以上。

2-Iodomelatonin可?于鉴定，表征和定位脑和周围组织的褪?激素结合位点。

REFERENCES

[1].TomkinsonA,etal.AmurineIL-4receptorantagonistthatinhibitsIL-4-andIL-13-inducedresponsespreventsantigen-inducedairway

eosinophiliaandairwayhyperresponsiveness.JImmunol.2001May1;166(9):5792-800.

[2].WangX,etal.ThemelatoninMT1receptoraxismodulatesmutantHuntingtin-mediatedtoxicity.JNeurosci.2011Oct12;31(41):14496-

507.

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