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Inhibitors?ScreeningLibraries?Proteins

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Tazarotene-13C6

Cat.No.:HY-15388S2

Synonyms:AGN190168-13C6

分?式:C????C?H??NO?S

分?量:354.39

作?靶点:Isotope-LabeledCompounds;RAR/RXR;Autophagy

作?通路:Others;MetabolicEnzyme/Protease;VitaminD

Related/NuclearReceptor;Autophagy

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Tazarotene-13C6(AGN190168-13C6)是13C标记的Tazarotene.Tazarotene(AGN190168)是选择性视黄酸

受体(RAR)激动剂，?于研究斑块状银屑病和寻常痤疮。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].NagpalS,etal.Negativeregulationoft