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Nadifloxacin-d5

Cat.No.:HY-B0506S1

Synonyms:OPC7251-d5

分?式:C??H??D?FN?O?

分?量:365.41

作?靶点:Isotope-LabeledCompounds;Antibiotic;Bacterial

作?通路:Others;Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Nadifloxacin-d5(OPC7251-d5)是氘代标记的Nadifloxacin.Nadifloxacin(OPC7251)是?谱的氟喹诺酮类抗?

素，对寻常粉刺有效。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].Jacobs,M.R.andP.C.Appelbaum,Nadifloxacin:aquinolonefortopicaltreatmentofskininfectionsandpotentialforsystemicuseofits

activeisomer,WCK771.Expert