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JTE-013(Standard)
Cat.No.:HY-100675R
CASNo.:383150-41-2
分?式:C??H??Cl?N?O
分?量:408.29
作?靶点:LPLReceptor;Apoptosis
作?通路:GPCR/GProtein;Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性JTE-013(Standard)是JTE-013的分析标准品。本产品?于研究及分析应?。JTE-013是?种有效且选择性的
S1P2(鞘氨醇1-磷酸2)拮抗剂。JTE-013抑制放射性标记的S1P与?和??S1P2的特异性结合，IC50分别为
17nM和22nM。
IC50TargetIC50:17nM(S1P2forhuman)and22nM(S1P2forrat)[1]
REFERENCES
[1].LiMH,etal.AntitumorActivityofaNovelSphingosine-1-Phosphate2Antagonist,AB1,inNeuroblastoma.JPharmacolExpTher.2015
Sep;354(3):261-8.
McePdfHeight
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