Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Goserelin-d10

Cat.No.:HY-13673S

Synonyms:ICI118630-d10

分?式:C??H??D??N??O??

分?量:1335.58

作?靶点:Isotope-LabeledCompounds

作?通路:Others

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Goserelin-d10(ICI118630-d10)是氘代标记的Goserelin.Goserelin(ICI118630)是?种促性腺激素释放激素(

GnRH/LHRH)?肽类似物，能作为GnRH激动剂。Goserelin可?于乳腺癌、上?性卵巢癌和前列腺癌的研究

[1][2]。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.