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Deltamethrin-d6

Cat.No.:HY-B1971S1

CASNo.:2483831-10-1

Synonyms:Decamethrin-d6

分?式:C??H??D?Br?NO?

分?量:511.24

作?靶点:Isotope-LabeledCompounds;Caspase;CalciumChannel;Bcl-

2Family;InterleukinRelated;NF-κB;Apoptosis;Endogenous

Metabolite

作?通路:Others;Apoptosis;MembraneTransporter/IonChannel;

NeuronalSignaling;Immunology/Inflammation;NF-κB;

MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Deltamethrin-d6(Decamethrin-d6)是氘代标记的Deltamethrin.Deltamethrin(Decamethrin)是?种具有?

服活性的??合成的拟除?菊酯类杀?剂。Deltamethrin通过抑制Nrf2/HO-1通路诱导氧化应激，导致炎症反

应和细胞凋亡(apoptosis)，通过诱导细胞凋亡(apoptosis)?发挥抗肿瘤作?，可?泛?于害?防治[1][2][3]

[4][5][6]。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.Impa