基本信息
文件名称:8-Oxo-dATP-生命科学试剂-MCE.pdf
文件大小:463.15 KB
总页数:1 页
更新时间:2025-05-21
总字数:约1.84千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

8-Oxo-dATP

Cat.No.:HY-172731

CASNo.:3056945-23-1

分?式:C??H??Li?N?O??P?

分?量:530.91

作?靶点:EndogenousMetabolite;NucleosideAntimetabolite/Analog

作?通路:MetabolicEnzyme/Protease;CellCycle/DNADamage

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性8-Oxo-dATP可通过氧化的嘌呤核苷三磷酸MTH1,?解为单磷酸盐,从?避免其在DNA复制或转录过程中发

?错误掺?所引发的错误。

REFERENCES

[1].YasunariSakai,etal.Amolecularbasisfortheselectiverecognitionof2-hydroxy-dATPand8-oxo-dGTPbyhumanMTH1.JBiolChem.

2002Mar8;277(10):8579-87.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您?边的抑制剂?师