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8-Oxo-dATP
Cat.No.:HY-172731
CASNo.:3056945-23-1
分?式:C??H??Li?N?O??P?
分?量:530.91
作?靶点:EndogenousMetabolite;NucleosideAntimetabolite/Analog
作?通路:MetabolicEnzyme/Protease;CellCycle/DNADamage
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性8-Oxo-dATP可通过氧化的嘌呤核苷三磷酸MTH1,?解为单磷酸盐,从?避免其在DNA复制或转录过程中发
?错误掺?所引发的错误。
REFERENCES
[1].YasunariSakai,etal.Amolecularbasisfortheselectiverecognitionof2-hydroxy-dATPand8-oxo-dGTPbyhumanMTH1.JBiolChem.
2002Mar8;277(10):8579-87.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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