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Inhibitors?ScreeningLibraries?Proteins

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Luliconazole-d3

Cat.No.:HY-14283S1

Synonyms:NND502-d3

分?式:C??H?D?Cl?N?S?

分?量:357.3

作?靶点:Isotope-LabeledCompounds;Antibiotic;Fungal

作?通路:Others;Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Luliconazole-d3(NND502-d3)是氘代标记的Luliconazole.Luliconazole(NND502)是?种咪唑类抗?素(

antibiotic)，具有?谱抗真菌活性。Luliconazole可?于?肤感染的研究，包括?肤真菌病、体癣、?癣等的

研究。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].HiroyasuKoga,etal.Short-termtherapywithluliconazole,anoveltopicalantifungalimidazol