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文件名称:Hedamycin-生命科学试剂-MCE.pdf
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文档摘要

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Hedamycin

Cat.No.:HY-N14671

CASNo.:11048-97-8

分?式:C??H??N?O??

分?量:746.84

作?靶点:Antibiotic;Bacterial

作?通路:Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Hedamycin是?种醌类抗?素,具有抗?兰?阳性菌、阴性菌、分枝杆菌和酵母菌活性(MIC为0.031-3.2μ

g/mL)。Hedamycin还能抑制????指肠腺癌、??Walker256肿瘤、HeLa细胞、?肠杆菌溶原性

W1709(λ)噬菌体。

REFERENCES

[1].LanChunTu,etal.Hedamycin,aDNAalkylator,induces(gamma)H2AXandchromosomeaberrations:involvementof

phosphatidylinositol3-kinase-relatedkinasesandDNAreplicationforkmovement.MolCancerTher.2005Aug;4(8):1175-85.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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