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文件名称:Cycloepoxydon-生命科学试剂-MCE.pdf
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Inhibitors?ScreeningLibraries?Proteins

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Cycloepoxydon

Cat.No.:HY-N14549

CASNo.:193481-66-2

分?式:C??H??O?

分?量:240.25

作?靶点:Phosphatase

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Cycloepoxydon抑制Phorbol12-myristate13-acetate(HY-18739)(PMA)诱导的NF-KB和AP-1介导的分泌

性碱性磷酸酶(SEAP)表达,IC50分别为1-2μg/mL(4.2-8.4μM)和3-5μg/mL(12.6-21μM)。

REFERENCES

[1].AGehrt,etal.Cycloepoxydon,1-hydroxy-2-hydroxymethyl-3-pent-1-enylbenzeneand1-hydroxy-2-hydroxymethyl-3-pent-1,3-

dienylbenzene,newinhibitorsofeukaryoticsignaltransduction.JAntibiot(Tokyo).1998May;51(5):455-63.

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