Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
Calpeptin(Standard)
Cat.No.:HY-100223R
CASNo.:117591-20-5
分?式:C??H??N?O?
分?量:362.46
作?靶点:Cathepsin;Proteasome;Apoptosis
作?通路:MetabolicEnzyme/Protease;Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Calpeptin(Standard)是Calpeptin的分析标准品。本产品?于研究及分析应?。Calpeptin是?种有效的、具
有细胞穿透性的calpain抑制剂，其对???板CalpainI的ID50值为40nM[1]。Calpeptin也是cathepsinK
的抑制剂[2]。
IC50TargetID50:40nM(CalpainIinhumanplatelets)[1].
CthepsinK[2]
REFERENCES
[1].TsujinakaT,etal.Synthesisofanewcellpenetratingcalpaininhibitor(calpeptin).BiochemBiophysResCommun.1988Jun
30;153(3):1201-8.
[2].CatalanoJG,etal.Designofsmallmoleculeketoamide-basedinhibitorsofcathepsinK.BioorgMedChemLett.2004Feb9;14(3):719-
22.
[3].TabataC,etal.Thecalpaininhibitorcalpeptinpreventspulmonaryfibrosisinmice.ClinExpImmunol.2010Dec;162(3):560-7.
McePdfHeight
Caution