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Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

TLK1-IN-1

Cat.No.:HY-173186

分?式:C??H??BrClN?O?

分?量:544.83

作?靶点:Ser/ThrKinase

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性TLK1-IN-1(Compound5n)是?种TLK1抑制剂，对TLK1B的IC50为7.2μM，对LNCaP细胞的GI50为2.7

μM。TLK1-IN-1诱导癌细胞DNA损伤和凋亡(Apoptosis)，可?于前列腺癌领域的研究[1]。

REFERENCES

[1].JohnsonD,etal.Characterizationofnewnon-ATPdependentinhibitorsofTLK1aspotentialmoleculesfortreatingprostatecancer.

BioorgChem.2025May;158:108317.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您?边的抑制剂?师