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Inhibitors?ScreeningLibraries?Proteins
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CDK2-IN-44
Cat.No.:HY-173310
CASNo.:3051587-93-7
分?式:C??H??F?N?O?S
分?量:467.53
作?靶点:CDK
作?通路:CellCycle/DNADamage
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性CDK2-IN-44(Compound46)是?种细胞周期蛋?依赖性激酶2(CDK2)的抑制剂。CDK2-IN-44能有效抑制癌
细胞增殖，通过使细胞周期停滞、促进细胞凋亡(Apoptosis)和诱导细胞衰?，从?发挥抑制癌细胞?长的活
性。CDK2-IN-44有望?于卵巢癌和乳腺癌的研究[1]。
IC50TargetCDK2
REFERENCES
[1].ChenW,etal.DiscoveryofpotentandselectiveCDK2inhibitorswithhighsafetyandfavorablebioavailabilityforthetreatmentof
cancer.EurJMedChem.2025Jun5;290:117503.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师