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Inhibitors?ScreeningLibraries?Proteins

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BAPTAtetrasodium(Standard)

Cat.No.:HY-100168AR

CASNo.:126824-24-6

分?式:C??H??N?Na?O??

分?量:564.36

作?靶点:Phospholipase

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性BAPTA(tetrasodium)(Standard)是BAPTA(tetrasodium)的分析标准品。本产品?于研究及分析应?。

BAPTAtetrasodium是?种选择性的钙离?螯合剂。BAPTAtetrasodium作为钙离?指?剂，对镁离?和钙离

?有较?的选择性。BAPTAtetrasodium被?泛?作细胞内缓冲液，?于研究通过质膜Ca2+透性通道从细胞

内存储或内流Ca2+释放的影响。BAPTAtetrasodium还可抑制磷脂酶C(phospholipaseC)的活性，与其钙

离?螯合特性?关。

REFERENCES

[1].RYTsien,etal.Newcalciumindicatorsandbufferswithhighselectivityagainstmagnesiumandprotons:design,synthesis,and

propertiesofprototypestructures.Biochemistry.1980May27;19(11):2396-404.

[2].RogerCHardie,etal.InhibitionofphospholipaseCactivityinDrosophilaphotoreceptorsby1,2-bis(2-aminophenoxy)ethaneN,N,N,N-

tetraaceticacid(BAPTA)anddi-bromoBAPTA.CellCalcium.2005Dec;38(6):547-56.

[3].MBCollatz,etal.IntracellularcalciumchelatorBAPT