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文件名称：Chlorpheniramine-d6-Chlorphenamine-d-sub-6-sub-生命科学试剂-MCE.pdf
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更新时间：2025-05-21
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文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Chlorpheniramine-d6

Cat.No.:HY-B0286S2

CASNo.:1185054-60-7

Synonyms:Chlorphenamine-d6

分?式:C??H??D?ClN?

分?量:280.83

作?靶点:Isotope-LabeledCompounds;HistamineReceptor

作?通路:Others;GPCR/GProtein;Immunology/Inflammation;Neuronal

Signaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Chlorpheniramine-d6(Chlorphenamine-d6)是氘代标记的Chlorpheniramine.Chlorpheniramine是过敏性疾

病常?的H1型抗组胺试剂。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].JiwonKim,etal.