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anti-NSCLCagent-1
Cat.No.:HY-173218
分?式:C??H??N?O?S
分?量:423.53
作?靶点:EGFR
作?通路:JAK/STATSignaling;ProteinTyrosineKinase/RTK
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性anti-NSCLCagent-1(compound8dc)是酪氨酸激酶抑制剂(TKI)的抑制剂,在A549和NCI-H441细胞中的
IC50值分别为0.05和0.09μM。anti-NSCLCagent-1在克隆形成、迁移和侵袭??表现出抗NSCLC活性
[1]。
REFERENCES
[1].JieZhang,etal;DiscoveryofnovelsmallmoleculestargetingTGF-βsignalingforthetreatmentofnon-smallcelllungcancer.EurJMed
Chem.2025May5:289:117442.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师