基本信息
文件名称:anti-NSCLC-agent-1-生命科学试剂-MCE.pdf
文件大小:459.74 KB
总页数:1 页
更新时间:2025-05-21
总字数:约1.88千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

anti-NSCLCagent-1

Cat.No.:HY-173218

分?式:C??H??N?O?S

分?量:423.53

作?靶点:EGFR

作?通路:JAK/STATSignaling;ProteinTyrosineKinase/RTK

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性anti-NSCLCagent-1(compound8dc)是酪氨酸激酶抑制剂(TKI)的抑制剂,在A549和NCI-H441细胞中的

IC50值分别为0.05和0.09μM。anti-NSCLCagent-1在克隆形成、迁移和侵袭??表现出抗NSCLC活性

[1]。

REFERENCES

[1].JieZhang,etal;DiscoveryofnovelsmallmoleculestargetingTGF-βsignalingforthetreatmentofnon-smallcelllungcancer.EurJMed

Chem.2025May5:289:117442.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师