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L-796778acetate
Cat.No.:HY-123335A
CASNo.:2922280-21-3
分?式:C??H??N?O?
分?量:644.72
作?靶点:SomatostatinReceptor
作?通路:GPCR/GProtein;NeuronalSignaling
储存?式:-20°C,storedundernitrogen,awayfrommoisture
*Insolvent:-80°C,6months;-20°C,1month(storedunder
nitrogen,awayfrommoisture)
BIOLOGICALACTIVITY
?物活性L-796778acetate是?种选择性的sst3受体激动剂。在表达hsst3受体的CHO-K1细胞中，L-796778acetate
是抑制Forskolin(HY-15371)刺激的cAMP产?的部分激动剂，其IC50值为18nM。L-796778acetate具有
抗惊厥作?[1]。
REFERENCES
[1].PfeifferM,etal.Homo-andheterodimerizationofsomatostatinreceptorsubtypes.Inactivationofsst(3)receptorfunctionby
heterodimerizationwithsst(2A).JBiolChem.2001Apr27;276(17):14027-36.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
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