基本信息
文件名称：JNJ525-生命科学试剂-MCE.pdf
文件大小：451.79 KB
总页数：1 页
更新时间：2025-05-21
总字数：约1.75千字
文档摘要
Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
JNJ525
Cat.No.:HY-124339
CASNo.:2092913-64-7
分?式:C??H??N?
分?量:514.62
作?靶点:TNFReceptor
作?通路:Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性JNJ525(compound1)是?种TNFα抑制剂，对TNFR1和TNFR2的IC50值分别为1.2μM和1.1μM。
REFERENCES
[1].BlevittJM,etal.StructuralBasisofSmall-MoleculeAggregateInducedInhibitionofaProtein-ProteinInteraction.JMedChem.2017Apr
27;60(8):3511-3517.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师