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Neuroprotectiveagent8

Cat.No.:HY-159928

分?式:C??H??NO?S?

分?量:381.55

作?靶点:ReactiveOxygenSpecies;PGC-1α;NOD-likeReceptor(NLR)

作?通路:Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Neuroprotectiveagent8(compoundAA-9)是?种具有?服活性的神经保护剂，通过抗氧化应激和抗炎作?

发挥功效。在??MCAO缺?性卒中模型中，Neuroprotectiveagent8可激活PGC-1α并抑制NLRP3炎症?

体。

REFERENCES

[1].ZhuC,etal.DiscoveryofneuroprotectiveAgents:Potent,brainPenetrating,lipoicacidderivativesforthepotentialtreatmentofischemic

strokebyregulatingoxidativestressandinflammation-aPreliminarystudy.BioorgChem.2024Jun;147:107339.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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