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Inhibitors?ScreeningLibraries?Proteins

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Mc-PEG4-Val-Ala-PAB-Exatecan

Cat.No.:HY-171580

分?式:C??H??FN?O??

分?量:1153.21

作?靶点:Drug-LinkerConjugatesforADC;Topoisomerase

作?通路:Antibody-drugConjugate/ADCRelated;CellCycle/DNA

Damage

储存?式:-20°C,sealedstorage,awayfrommoistureandlight

*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoistureandlight)

BIOLOGICALACTIVITY

?物活性Mc-PEG4-Val-Ala-PAB-Exatecan是?种ADC药物-连接?偶联物(Drug-linkerconjugateforADC)。Mc-PEG4-

Val-Ala-PAB-Exatecan含有ADC连接物(Mc-PEG4-Val-Ala-PAB)和DNAtopoisomeraseI抑制剂Exatecan

(HY-13631)。

REFERENCES

[1].SchmittS,etal.DesignandEvaluationofPhosphonamidate-LinkedExatecanConstructsforHighlyLoaded,Stable,andEfficacious

Antibody-DrugConjugates.MolCancerTher.2024Feb1;23(2):199-211.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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