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Inhibitors?ScreeningLibraries?Proteins

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Glucosamine-13C6

Cat.No.:HY-B1125S

Synonyms:D-Glucosamine-13C;Chitosamine-13C

66

分?式:C??H?NO?

分?量:1003.88

作?靶点:Isotope-LabeledCompounds;CFTR;HIF/HIFProlyl-

Hydroxylase;ReactiveOxygenSpecies;Endogenous

Metabolite;Autophagy

作?通路:Others;MembraneTransporter/IonChannel;Metabolic

Enzyme/Protease;Immunology/Inflammation;NF-κB;

Autophagy

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Glucosamine-13C6(D-Glucosamine-13C6)是13C标记的Glucosamine.Glucosamine(D-Glucosamine)是?

种氨基糖,是糖基化蛋?和脂质?化合成的突出前体,?作膳?补充剂。Glucosamine也是软?基质和滑液中糖

胺聚糖的天然成分，当外?时，对?关节炎软?和软?细胞具有药理作?。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokinetic