基本信息
文件名称：Brivudine-13C-15N2-Bromovinyldeoxyuridine-sup-13-sup-C-sup-15-sup-N-sub-2-sub-生命科学试剂-MCE.pdf
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更新时间：2025-05-21
总字数：约2.74千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Brivudine-13C,15N2

Cat.No.:HY-13578S

Synonyms:Bromovinyldeoxyuridine-13C,15N;BVDU-13C,15N

22

分?式:C????CH??Br??N?O?

分?量:336.11

作?靶点:Isotope-LabeledCompounds;CMV

作?通路:Others;Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Brivudine-13C,15N2(Bromovinyldeoxyuridine-13C,15N2)是13C和15N标记的Brivudine.Brivudine是具

有抗病毒活性的胸苷类似物,?于早期急性带状疱疹的研究。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].RabassedaX,etal.Br