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Inhibitors?ScreeningLibraries?Proteins

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Furegrelatesodium(Standard)

Cat.No.:HY-106080AR

CASNo.:85666-17-7

Synonyms:U-63557A(Standard)

分?式:C??H??NNaO?

分?量:275.23

作?靶点:ProstaglandinReceptor

作?通路:GPCR/GProtein

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Furegrelate(sodium)(Standard)是Furegrelate(sodium)的分析标准品。本产品?于研究及分析应?。

FuregrelateSodium(U-63557A)是?种有效的、?服的、选择性的?栓素合酶(thromboxanesynthase)抑制

剂。FuregrelateSodium抑制???板微粒体?栓素A2(TxA2)合酶，其IC50为15nM。Furegrelate

Sodium正在开发作为抗??板活性分?。

REFERENCES

[1].GormanRR,etal.InhibitionofplateletthromboxaneA2synthaseactivitybysodium5-(3-pyridinylmethyl)benzofuran-2-carboxylate.

Prostaglandins.1983Aug;26(2):325-42.

[2].Hirenallur-SDK,etal.Furegrelate,athromboxanesynthaseinhibitor,bluntsthedevelopmentofpulmonaryarterialhypertensionin

neonatalpiglets.PulmCirc.2012Apr-Jun;2(2):193-200.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.