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文件名称:2-Methyl-estradiol-生命科学试剂-MCE.pdf
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更新时间:2025-05-21
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文档摘要

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2-Methylestradiol

Cat.No.:HY-W702106

CASNo.:1818-12-8

分?式:C??H??O?

分?量:286.41

作?靶点:EndogenousMetabolite

作?通路:MetabolicEnzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性2-Methylestradiol是雌?醇(HY-B0141)的内源性代谢物,能抑制细胞增殖和?管?成,对HUVEC(?脐静脉

内?细胞)和MCF-7(?乳腺癌细胞)的增殖的IC50值分别为3μM和2.39μM。

REFERENCES

[1].IljungLee,etal.2-[methyl-(11)C]methoxyestradiol:synthesis,evaluationandpharmacokineticsforinvivostudiesonangiogenesis.Nucl

MedBiol.2007Aug;34(6):625-31.

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