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Inhibitors?ScreeningLibraries?Proteins
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VEGFR-2-IN-66
Cat.No.:HY-173232
分?式:C??H??N?O?
分?量:422.44
作?靶点:VEGFR;Apoptosis
作?通路:ProteinTyrosineKinase/RTK;Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性VEGFR-2-IN-66(Compound6)是?种具有?服活性的VEGFR-2抑制剂，IC50值为0.509μM，对MCF-7细胞
增殖抑制IC50值为7.48μM。VEGFR-2-IN-66通过阻滞细胞周期、诱导凋亡(Apoptosis)、调节基因表达来发
挥抗癌活性，可?于乳腺癌领域的研究[1]。
IC50TargetVEGFR2
509nM(IC50)
REFERENCES
[1].MabroukRR,etal.NoveltriazoloquinazolinederivativesasVEGFRinhibitors:synthesis,cytotoxicevaluationandinsilicostudies.
FutureMedChem.2025Mar;17(5):529-541.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师