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TUG-2181
Cat.No.:HY-176039
CASNo.:2653994-24-0
分?式:C??H??NO?
分?量:357.44
作?靶点:GPR84;ReactiveOxygenSpecies
作?通路:GPCR/GProtein;Immunology/Inflammation;Metabolic
Enzyme/Protease;NF-κB
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性TUG-2181是GPR84的拮抗剂，IC50值为34nM。TUG-2181在?中性粒细胞中可抑制GPR84激动剂诱导的
活性氧(ROS)和IL-8分泌。TUG-2181可?于炎症和纤维化的研究[1]。
REFERENCES
[1].IeremiasL,etal.MinimalStructuralVariationofGPR84FullAgonistCausesFunctionalSwitchtoInverseAgonism.JMedChem.2025
Apr4.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师