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Sulfamerazine-13C6

Cat.No.:HY-B0512S1

CASNo.:1196157-80-8

Synonyms:RP2632-13C6

分?式:C???C?H??N?O?S

分?量:270.26

作?靶点:Isotope-LabeledCompounds;Bacterial;Antibiotic

作?通路:Others;Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Sulfamerazine-13C6(RP2632-13C6)是13C标记的Sulfamerazine(HY-B0512).Sulfamerazine(RP-2632)是磺

胺类抗菌素。Sulfamerazine(RP-2632)是磺胺嘧啶的单甲基衍?物，是2-磺胺基-4-甲基嘧啶。

Sulfamerazine(RP-2632)是?种磺胺类活性分?，通过与对氨基苯甲酸(PABA)竞争结合?氢叶酸合成，抑制

细菌合成?氢叶酸。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019