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Lansoprazolesulfone-13C6

Cat.No.:HY-W008614S1

CASNo.:1261398-50-8

Synonyms:AG-1813-13C6

分?式:C????C?H??F?N?O?S

分?量:391.32

作?靶点:Isotope-LabeledCompounds;ProtonPump;DrugMetabolite

作?通路:Others;MembraneTransporter/IonChannel;Metabolic

Enzyme/Protease

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Lansoprazolesulfone-13C6(AG-1813-13C6)是13C标记的Lansoprazolesulfone.Lansoprazolesulfone

(AG-1813)是?种具有?服活性和选择性的H+,K+-ATPase抑制剂。Lansoprazolesulfone通过抑制H+,K+-

ATPase，可显著刺激胃酸分泌。Lansoprazolesulfone在??指肠溃疡、胃溃疡、胃?管反流性疾病和卓艾综

合症中有潜在应?。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

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