基本信息
文件名称：Equilin-d2-7-Dehydroestrone-d-sub-2-sub-生命科学试剂-MCE.pdf
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更新时间：2025-05-22
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文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Equilin-d2

Cat.No.:HY-B1176S1

Synonyms:7-Dehydroestrone-d2

分?式:C??H??D?O?

分?量:270.36

作?靶点:Isotope-LabeledCompounds;EstrogenReceptor/ERR

作?通路:Others;VitaminDRelated/NuclearReceptor

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Equilin-d2(7-Dehydroestrone-d2)是氘代标记的Equilin.Equilin(7-Dehydroestrone)是??类雌激素物质中

的重要成员，与雌?醇有化学关系。Equilin通过NMDA受体依赖机制促进?层神经元的?长。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].DavidK,etal.Somebiologicalpropertiesofequilin.BiochemJ.1935;29(2):371-377.