Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
CGS15943(Standard)
Cat.No.:HY-100678R
CASNo.:104615-18-1
分?式:C??H?ClN?O
分?量:285.69
作?靶点:AdenosineReceptor;PI3K
作?通路:GPCR/GProtein;PI3K/Akt/mTOR
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性CGS15943(Standard)是CGS15943的分析标准品。本产品?于研究及分析应?。CGS15943是adenosine
receptor腺苷受体的?黄嘌呤拮抗剂，具有?服活性。接受?重组A1，A2A，A2B和A3受体转染的CHO细
胞中，Ki值分别为3.5、4.2、16和50nM。
REFERENCES
[1].GaoY,etal.CGS15943,anadenosineA2receptorantagonist,reducescerebralischemicinjuryintheMongoliangerbil.LifeSci.
1994;55(3):PL61-5.
[2].KlotzKN,etal.Adenosinereceptorsandtheirligands.NaunynSchmiedebergsArchPharmacol.2000Nov;362(4-5):382-91.
[3].EdlingCE,etal.CaffeineandtheanalogCGS15943inhibitcancercellgrowthbytargetingthephosphoinositide3-kinase/Aktpathway.
CancerBiolTher.2014May;15(5):524-32.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.