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文件名称:Tryptophol-d4-Indole-3-ethanol-d-sub-4-sub-生命科学试剂-MCE.pdf
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文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Tryptophol-d4

Cat.No.:HY-W750342

CASNo.:75238-45-8

Synonyms:Indole-3-ethanol-d

4

分?式:C??H?D?NO

分?量:165.23

作?靶点:Isotope-LabeledCompounds;EndogenousMetabolite;

Apoptosis;Caspase;Bacterial

作?通路:Others;MetabolicEnzyme/Protease;Apoptosis;Anti-infection

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Tryptophol-d4(Indole-3-ethanol-d4)是氘标记的Tryptophol(HY-W010155)。Tryptophol是?种芳?醇和微

?物产?的次级代谢产物。Tryptophol诱导凋亡(apoptosis)和caspase-8切割。Tryptophol抑制

Cunninghamellablakesleeana?物膜。Tryptophol具有抗噬菌体感染、调节?物膜形成、抗炎、溶?、诱导

睡眠、改变体温、影响惊厥易感性以及调节免疫等活性。Tryptophol?于?洲锥?病、睡眠障碍、癫痫等疾病

的相关研究。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention