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Inhibitors?ScreeningLibraries?Proteins
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Tryptophol-d4
Cat.No.:HY-W750342
CASNo.:75238-45-8
Synonyms:Indole-3-ethanol-d
4
分?式:C??H?D?NO
分?量:165.23
作?靶点:Isotope-LabeledCompounds;EndogenousMetabolite;
Apoptosis;Caspase;Bacterial
作?通路:Others;MetabolicEnzyme/Protease;Apoptosis;Anti-infection
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Tryptophol-d4(Indole-3-ethanol-d4)是氘标记的Tryptophol(HY-W010155)。Tryptophol是?种芳?醇和微
?物产?的次级代谢产物。Tryptophol诱导凋亡(apoptosis)和caspase-8切割。Tryptophol抑制
Cunninghamellablakesleeana?物膜。Tryptophol具有抗噬菌体感染、调节?物膜形成、抗炎、溶?、诱导
睡眠、改变体温、影响惊厥易感性以及调节免疫等活性。Tryptophol?于?洲锥?病、睡眠障碍、癫痫等疾病
的相关研究。
体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,
largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention