基本信息
文件名称:Taurine-15N-2-Aminoethanesulfonic-acid-sub-15-sub-N-sub-生命科学试剂-MCE.pdf
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文档摘要

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Taurine-15N

Cat.No.:HY-W727893

CASNo.:127041-63-8

Synonyms:2-Aminoethanesulfonicacid-15N

分?式:C?H???NO?S

分?量:126.14

作?靶点:Isotope-LabeledCompounds;EndogenousMetabolite;

Autophagy

作?通路:Others;MetabolicEnzyme/Protease;Autophagy

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Taurine-15N(2-Aminoethanesulfonicacid-15N)是15N标记的Taurine.Taurine是?种含硫氨基酸和?种参

与细胞体积调节的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度??发挥作?。

Taurine有激活脂肪细胞?噬(autophagy)的能?。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacot