Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
Taurine-15N
Cat.No.:HY-W727893
CASNo.:127041-63-8
Synonyms:2-Aminoethanesulfonicacid-15N
分?式:C?H???NO?S
分?量:126.14
作?靶点:Isotope-LabeledCompounds;EndogenousMetabolite;
Autophagy
作?通路:Others;MetabolicEnzyme/Protease;Autophagy
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Taurine-15N(2-Aminoethanesulfonicacid-15N)是15N标记的Taurine.Taurine是?种含硫氨基酸和?种参
与细胞体积调节的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度??发挥作?。
Taurine有激活脂肪细胞?噬(autophagy)的能?。
体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,
largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention
becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.
REFERENCES
[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacot