Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
PBP4-IN-1
Cat.No.:HY-173197
分?式:C??H??ClN?O?
分?量:371.86
作?靶点:Bacterial
作?通路:Anti-infection
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性PBP4-IN-1(Compound1)是?种?黄?葡萄球菌青霉素结合蛋?4(PBP4)抑制剂。PBP4-IN-1通过抑制PBP4
功能，发挥增强抗?素对PBP2a介导的耐甲氧西林?黄?葡萄球菌(MRSA)的抑制活性。PBP4-IN-1可?于研
究?黄?葡萄球菌引起的?髓炎，以及?于研究逆转PBP4介导的β-内酰胺类抗?素耐药性等[1]。
REFERENCES
[1].ButmanHS,etal.Phenylureabasedadjuvantsforβ-lactamantibioticsagainstmethicillinresistantStaphylococcusaureus.BioorgMed
ChemLett.2025Jun1;121:130164.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE
1/1MasterofBioactiveMolecules—您?边的抑制剂?师