TraditionalChineseMedicineChemistry
TeachingscheduleTopicsTeachingContentsChapters*LectureHoursFormofTeachingClass1introductionChapter13BAILI-PINGClass2ThegeneralresearchmethodofchemicalcompositionofChinesemedicineChapter23BAILI-PINGClass3flavonoidsChapter69LINAClass4SugarandglycosidesChapter33WANGJING-RONGClass5PhenylalanineChapter56LINAClass6quinonesChapter43LINAClass7期中考试(29March)?3?Class8alkaloidsChapter109BAILI-PINGClass9TerpenoidsandvolatileoilsChapter73WANGJING-RONGClass10diterpenoidsChapter73LINAClass11Triterpenoidsandsaponins,steroidandcardiosideChapter8,96BAILI-PINGClass12tanninsChapter113JIANGZHI-HONGClass13AnimalmedicinechemicalcompositionChapter123JIANGZHI-HONGClass10OthercompositionChapter123LINA
ClassParticipation20%Midterm20%Finalexam60%Total100%BibliographyAssessmentMethodTextbook(s):中药化学,何昱主编,科学出版社,2017年6月第1版YuHe.ChineseMedicineChemistry(Ed.1).SciencePress.(2017-06)
Flavonoids(1)分类和性质
CONTENTsummarize1Structureandclassificationofflavonoids2physicochemicalpropertyofflavonoids3extractionandseparationofflavonoids4Structureandclassificationofflavonoids5
CONTENTFlavonoidsareakindofimportantheterocyclicnaturalorganiccompounds.FlavonoidsareAseriesofcompoundsthatareformedbythecentraltricarbonatomsoftwobenzenerings(a-andb-rings)。Distribution:commoninhigherplantsForms:aglycones,glycosidesVariousactivities:anti-oxidation,cardiovascularprotection,liverprotection,anti-inflammation,anti-cancer,andsimilarestrogeneffectsAB
Basicstructurenucleus:9(8a)10(4a)
Biosynthesisfundamentalways黄酮的基本骨架是由三个PropyleneDiacetylCoA和一个CinnamicCoenzymeA生物合成而产生的。A环来自于三个PropyleneDiacetylCoA,而B环则来自于CinnamicCoenzymeA。
FlavonoidglycosidesyuanSubstituents:OH,OMe,Me,isopentenylandsoonFlavonoidglycosidesOxygeninandcarbolicform
contentsummarize1Structureandclassificationofflavonoids2physicochemicalprop