基本信息
文件名称：CypB-IN-1-生命科学试剂-MCE.pdf
文件大小：466.32 KB
总页数：1 页
更新时间：2025-05-22
总字数：约1.84千字
文档摘要
Hotline:400-820-3792
Inhibitors?ScreeningLibraries?Proteins
www.MedChemE
CypB-IN-1
Cat.No.:HY-173265
分?式:C??H??ClN?O?S
分?量:529.06
作?靶点:Cyclophilin
作?通路:Immunology/Inflammation
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性CypB-IN-1(Compound11)是?种亲环蛋?B(cyclophilinB)的抑制剂，Kd值为12nM。CypB-IN-1可?于代
谢功能障碍相关脂肪性肝炎(MASH)及其导致的肝纤维化疾病领域的研究[1]。
IC50TargetCyclophilinB
REFERENCES
[1].KouridakiME,etal.OptimizationofCyclophilinB-TargetedTri-vectorInhibitorsforNovelMASHTreatments.JMedChem.2025Mar
27;68(6):6815-6831.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师