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5,7-Dichlorokynurenicacid(Standard)

Cat.No.:HY-100834R

CASNo.:131123-76-7

Synonyms:5,7-DCKA(Standard)

分?式:C??H?Cl?NO?

分?量:258.06

作?靶点:iGluR

作?通路:MembraneTransporter/IonChannel;NeuronalSignaling

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性5,7-Dichlorokynurenicacid(Standard)是5,7-Dichlorokynurenicacid的分析标准品。本产品?于研究及分析

应?。5,7-Dichlorokynurenicacid(5,7-DCKA)是?种选择性的NMDA受体?氨酸位点竞争性拮抗剂，KB值

为65nM。5,7-Dichlorokynurenicacid是?尿酸的衍?物，可减少???质细胞培养物中NMDA诱导的神经

元损伤。

REFERENCES

[1].DMcNamara,etal.5,7-Dichlorokynurenicacid,apotentandselectivecompetitiveantagonistoftheglycinesiteonNMDAreceptors.

NeurosciLett.1990Nov27;120(1):17-20.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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