基本信息
文件名称:CDK2-IN-43-生命科学试剂-MCE.pdf
文件大小:456.53 KB
总页数:1 页
更新时间:2025-05-22
总字数:约1.84千字
文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

CDK2-IN-43

Cat.No.:HY-173203

分?式:C??H??N?O

分?量:369.46

作?靶点:CDK

作?通路:CellCycle/DNADamage

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性CDK2-IN-43(Compound3a)是?种CDK2-cyclinE2抑制剂,IC50值为6.0nM。CDK2-IN-43可?于抗癌领域

的研究[1]。

IC50TargetCdk2/cyclinE2

6nM(IC50)

REFERENCES

[1].ZhangY,etal.Developmentof9H-purinescaffoldasnovelCDK2inhibitors:Design,synthesis,andbiologicalevaluation.BioorgMed

ChemLett.2025Mar7;122:130166.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您?边的抑制剂?师