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nNOS-IN-5
Cat.No.:HY-170236
CASNo.:2945955-27-9
分?式:C??H??N?O
分?量:370.45
作?靶点:NOSynthase
作?通路:Immunology/Inflammation
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性nNOS-IN-5(Compound9)是?种有效的?神经元型?氧化氮合酶(nNOS)抑制剂(Ki=22nM)。nNOS-IN-5表
现出优异的选择性,对?nNOS的选择性?对?内?型?氧化氮合酶(eNOS)的选择性?900倍。nNOS-IN-5
可?于神经退?性疾病的研究,如阿尔茨海默病和帕?森病[1]。
REFERENCES
[1].WeerawarnaPM,etal.ATetrahydrobiopterin-DisplacingPotentNeuronalNitricOxideSynthaseInhibitorwithanUnprecedented
BindingMode.ACSMedChemLett.2025Mar21;16(4):651-659.
McePdfHeight
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师