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Inhibitors?ScreeningLibraries?Proteins
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Lipohexin
Cat.No.:HY-N5194
CASNo.:193751-58-5
分?式:C??H??N?O?
分?量:764.99
作?靶点:Antibiotic;Bacterial;ProlylEndopeptidase(PREP)
作?通路:Anti-infection;MetabolicEnzyme/Protease
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性Lipohexin是?种肽类抗?素。Lipohexin具有抗?兰?阳性菌作?。Lipohexin对?胎盘脯氨酸内肽酶(
prolineendopeptidase)有竞争性抑制作?,IC50为3.5μM。Lipohexin抑制脑膜炎黄杆菌的脯氨酸内肽酶,
IC50为25μM。
REFERENCES
[1].SHeinze,etal.Lipohexin,anewinhibitorofprolylendopeptidasefromMoeszialindtneri(HKI-0054)andPaecilomycessp.(HKI-0055;
HKI-0096).I.Screening,isolationandstructureelucidation.JAntibiot(Tokyo).1997May;50(5):379-83.
McePdfHeight
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