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Inhibitors?ScreeningLibraries?Proteins
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BMX-IN-3
Cat.No.:HY-173057
CASNo.:2657662-64-9
分?式:C??H??N?O?S
分?量:467.54
作?靶点:BMXKinase;Apoptosis;Autophagy
作?通路:ProteinTyrosineKinase/RTK;Apoptosis;Autophagy
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性BMX-IN-3(B6a)是?种不可逆且选择性的BMX抑制剂，其IC50为12nM。BMX-IN-3(B6a)促进细胞周期停滞
和凋亡，触发保护性?噬，并抑制BMX/AKT/mTOR途径。BMX-IN-3(B6a)可?于胃癌研究。
REFERENCES
[1].NanWang,Design,Synthesis,andMechanismStudyofNovelBMXInhibitorsBasedontheCoreof1,3,5-Triazin-2-Amineforthe
TreatmentofGastricCarcinoma.JMedChem.2025Feb27;68(4):4196-4216.
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1/1MasterofBioactiveMolecules—您?边的抑制剂?师