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(S,R,S)-AHPC-Bocderivative1

Cat.No.:HY-173097

CASNo.:2086298-33-9

Synonyms:VH032-Bocderivative1

分?式:C??H??N?O?S

分?量:560.71

作?靶点:MALT1

作?通路:MetabolicEnzyme/Protease;NF-κB

储存?式:Powder-20°C3years

Insolvent-80°C6months

-20°C1month

溶解性数据

体外实验DMSO:50mg/mL(89.17mM;Needultrasonic)

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM1.7835mL8.9173mL17.8345mL

5mM0.3567mL1.7835mL3.5669mL

10mM0.1783mL0.8917mL1.7835mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；?旦配成溶液，请分装保存，避免反复冻融造

成的产品失效。储备液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C储存时，请在6个?

内使?，-20°C储存时，请在1个?内使?。

BIOLOGICALACTIVITY

?物活性(S,R,S)-AHPC-Bocderivative1(Compound80-9;VH032-Bocderivative1)是?种选择性蛋?酶体降解物，靶

向MALT1，招募E3泛素连接酶CRBN与MALT1形成三元复合物，导致MALT1泛素化并随后蛋?酶体降解。

(S,R,S)-AHPC-Bocderivat