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文件名称:Quercetin-4-Glucoside-d3-Spiraeoside-d-sub-3-sub-生命科学试剂-MCE.pdf
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更新时间:2025-05-23
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文档摘要

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

Quercetin4-Glucoside-d3

Cat.No.:HY-N8253S

Synonyms:Spiraeoside-d3

分?式:C??H??D?O??

分?量:466.39

作?靶点:Isotope-LabeledCompounds;ReactiveOxygenSpecies

作?通路:Others;Immunology/Inflammation;Metabolic

Enzyme/Protease;NF-κB

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性Quercetin4-Glucoside-d3(Spiraeoside-d3)是氘代标记的Spiraeoside.Spiraeoside是具有?服活性的天然产

物,具有抗氧化活性,抑制活性氧和丙?醛的?成。Spiraeoside具有抗过敏、抗炎、抗肿瘤活性。

体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,

largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattention

becauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.

REFERENCES

[1].RussakEM,etal.ImpactofDeuteriumSubstitutiononthePharmacokineticsofPharmaceuticals.AnnPharmacother.2019;53(2):211-

216.

[2].HongyangLiu,etal.Spiraeosideprotectshumancardiomy