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Inhibitors?ScreeningLibraries?Proteins
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ODQ(Standard)
Cat.No.:HY-101255R
CASNo.:41443-28-1
分?式:C?H?N?O?
分?量:187.16
作?靶点:GuanylateCyclase;Apoptosis
作?通路:GPCR/GProtein;Apoptosis
储存?式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
?物活性ODQ(Standard)是ODQ的分析标准品。本产品?于研究及分析应?。ODQ是?种有效的选择性可溶性鸟苷酰
环化酶(sGC)抑制剂。ODQ增强顺铂促?间?瘤细胞凋亡的作?。
REFERENCES
[1].RonaldFiscus,etal.ODQ,aninhibitorofsolubleguanylylcyclase(nitricoxide-activatedenzyme),enhancesthepro-apoptoticeffectsof
cisplatininhumanmesotheliomacells.CancerResMay12007(67)(9Supplement)LB-43.
[2].ZacharowskiK,etal.TheselectiveguanylatecyclaseinhibitorODQreducesmultipleorganinjuryinrodentmodelsofGram-positiveand
Gram-negativeshock.CritCareMed.2001;29(8):1599-1608.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
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