基本信息
文件名称:NPPB-Standard-生命科学试剂-MCE.pdf
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更新时间:2025-05-23
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文档摘要

Hotline:400-820-3792

Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

NPPB(Standard)

Cat.No.:HY-101012R

CASNo.:107254-86-4

分?式:C??H??N?O?

分?量:300.31

作?靶点:ChlorideChannel

作?通路:MembraneTransporter/IonChannel

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性NPPB(Standard)是NPPB的分析标准品。本产品?于研究及分析应?。NPPB是外向整流氯化物通道(ORCC)

的阻断剂。

IC50TargetORCC[1]

REFERENCES

[1].LiJ,etal.Enhancementofanoutwardlyrectifyingchloridechannelinhippocampalpyramidalneuronsaftercerebralischemia.Brain

Res.2016Aug1;1644:107-17.

[2].ParkM,etal.DoubleBlockadeofGliomaCellProliferationandMigrationbyTemozolomideConjugatedwithNPPB,aChlorideChannel

Blocker.ACSChemNeurosci.2016Mar16;7(3):275-85.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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